Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | TPH1 | P17752 | 5/20 | 0.44 |
| ▸ | GRB2 | P62993 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL27709789 | 0.90 | SLC7A5 (0.67) | SLC7A5PTGS1ALPIPKMXIAP | |
| Phenylalanine SCHEMBL11133474 | 0.90 | SLC7A5 (0.65) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL28813646 | 0.87 | SLC7A5 (0.61) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL1079463 | 0.85 | ALPI (0.56) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL2515423 | 0.85 | ALPI (0.56) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL1692431 | 0.85 | ALPI (0.56) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL1827246 | 0.84 | SLC7A5 (0.50) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL1827244 | 0.84 | SLC7A5 (0.50) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL4268012 | 0.84 | ALDH1A1 (0.42) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL607242 | 0.84 | SLC7A5 (0.56) | SLC7A5KDM4EHSD17B10CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190127315-A1 | METHOD FOR PREPARING D-4,4'-BIPHENYLALANINE ALKYL ESTER OR L-4,4'-BIPHENYLALANINE ALKYL ESTER FROM DL-4,4'-BIPHENYLALANINE ALKYL ESTER | AMINOLOGICS CO., LTD. (KR) | 2019-05-02 | — | — | US | claimed |
| US-20190127315-A1 | METHOD FOR PREPARING D-4,4'-BIPHENYLALANINE ALKYL ESTER OR L-4,4'-BIPHENYLALANINE ALKYL ESTER FROM DL-4,4'-BIPHENYLALANINE ALKYL ESTER | AMINOLOGICS CO., LTD. (KR) | 2019-05-02 | — | — | US | disclosed |
| US-20190127315-A1 | METHOD FOR PREPARING D-4,4'-BIPHENYLALANINE ALKYL ESTER OR L-4,4'-BIPHENYLALANINE ALKYL ESTER FROM DL-4,4'-BIPHENYLALANINE ALKYL ESTER | AMINOLOGICS CO., LTD. (KR) | 2019-05-02 | — | — | US | disclosed |
| WO-2017183835-A1 | METHOD FOR PREPARING D-4,4'-BIPHENYLALANINE ALKYL ESTER OR L-4,4'-BIPHENYLALANINE ALKYL ESTER FROM DL-4,4'-BIPHENYLALANINE ALKYL ESTER | 주식회사 아미노로직스 | 2017-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127315-A1 | METHOD FOR PREPARING D-4,4'-BIPHENYLALANINE ALKYL ESTER OR L-4,4'-BIPHENYLALANINE ALKYL ESTER FROM DL-4,4'-BIPHENYLALANINE ALKYL ESTER | DDT, DLST, LPAR4 | SLC7A5 674/4885PTGS1 4785/4885ALPI 4205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.