Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | XIAP | P98170 | 1/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.56 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1079463 | 1.00 | ALPI (0.56) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL1692431 | 1.00 | ALPI (0.56) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine SCHEMBL11133474 | 0.95 | SLC7A5 (0.65) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Pyrrole SCHEMBL28176452 | 0.93 | ALPI (0.49) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL10458393 | 0.93 | ALPI (0.49) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Tyrosine SCHEMBL28813646 | 0.89 | SLC7A5 (0.61) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL4268012 | 0.86 | ALDH1A1 (0.42) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL607242 | 0.86 | SLC7A5 (0.56) | SLC7A5CYP3A4ALDH1A1HSD17B10HDAC8 | |
| SCHEMBL598432 | 0.86 | SLC7A5 (0.56) | SLC7A5CYP3A4ALDH1A1HSD17B10HDAC8 | |
| SCHEMBL19472012 | 0.85 | SLC7A5 (0.51) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585142-B | Novel antimalarial compounds, method for the production thereof and use thereof for the resistance of malaria | 科学与工业研究会 | 2024-01-19 | — | — | CN | claimed |
| CN-112585142-A | Novel antimalarial compounds, preparation method and use thereof for drug-resistant malaria | 科学与工业研究会 | 2021-03-30 | — | — | CN | claimed |
| WO-2008096373-A2 | PROCESS FOR SYNTHESIZING HIGHLY PURE NATEGLINIDE POLYMORPHS | IND-SWIFT LABORATORIES LIMITED (IN) | 2008-08-14 | — | — | WO | claimed |
| EP-0074095-B1 | PROCESS FOR PREPARATION OF ASPARTYLPHENYLALANINE ALKYL ESTERS | TOYO SODA MANUFACTURING CO., LTD. (JP) | 1986-04-30 | — | — | EP | claimed |
| US-3983162-A | Optical resolution of alkyl esters of DL-phenylalanine | G. D. SEARLE & CO. (US) | 1976-09-28 | — | — | US | claimed |
| JP-9248197-A | — | — | None | — | — | JP | disclosed |
| JP-54061140-A | — | — | None | — | — | JP | disclosed |
| JP-6107631-A | — | — | None | — | — | JP | disclosed |
| JP-1160495-A | — | — | None | — | — | JP | disclosed |
| JP-6157466-A | — | — | None | — | — | JP | disclosed |
| EP-3015488-B1 | PRODUCTION METHOD FOR POLYAMINO ACID | TAKEDA PHARMACEUTICALS CO (JP) | 2024-03-06 | — | — | EP | disclosed |
| CN-112585142-B | Novel antimalarial compounds, method for the production thereof and use thereof for the resistance of malaria | 科学与工业研究会 | 2024-01-19 | — | — | CN | disclosed |
| WO-1985003932-A1 | NOVEL DIASTEREOMER SALTS OF PHENYLALANINE AND N-ACYL DERIVATIVES THEREOF AND PROCESS FOR THE SEPARATION OF OPTICALLY ACTIVE PHENYLALANINE AND N-ACYL DERIVATIVES THEREOF | ALKALOIDA VEGYÉSZETI GYÁR (HU) | 1985-09-12 | — | — | WO | disclosed |
| EP-0143881-A2 | Process for the preparation of an alkyl ester of L-alpha-aspartyl-L-phenyl-alanine | GEMA S.A. (ES) | 1985-06-12 | — | — | EP | disclosed |
| US-4436925-A | Addition compound of dipeptide derivative and amino acid derivative | TOYO SODA MANUFACTURING CO., LTD. (JP) | 1984-03-13 | — | — | US | disclosed |
| US-4256836-A | REACTING AN N-SUBSTITUTED MONOAMINODICARBOXYLIC ACID WITH AN AMINO CARBOXYLIC ACID ESTER | TOYO SODA MANUFACTURING CO. LTD. (JP) | 1981-03-17 | — | — | US | disclosed |
| US-4165311-A | Addition compound of dipeptide derivative and amino acid derivative | TOYO SODA MANUFACTURING CO. LTD. (JP) | 1979-08-21 | — | — | US | disclosed |
| JP-S5461140-A | PREPARATION OF ALPHA-ASPARTYL-PHENYLALANINE ALKYL ESTER | TOYO SODA MFG CO LTD | 1979-05-17 | — | — | JP | disclosed |
| US-3941831-A | Resolution of alkyl esters of DL-phenylalanine | G. D. SEARLE & CO. (US) | 1976-03-02 | — | — | US | disclosed |
| US-3941831-A | Resolution of alkyl esters of DL-phenylalanine | G. D. SEARLE & CO. (US) | 1976-03-02 | — | — | US | disclosed |