Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4909640 | 0.91 | TLR7 (0.43) | TLR7MEN1USP2MAPTALOX15 | |
| SCHEMBL10798028 | 0.89 | TLR7 (0.44) | TLR7MEN1MAPTKMT2ATLR8 | |
| SCHEMBL4912349 | 0.87 | TLR7 (0.46) | TLR7MEN1KMT2AGPBAR1NPC1 | |
| SCHEMBL10798009 | 0.81 | TDP1 (0.52) | TLR7MAPTGPBAR1KDM4ENPC1 | |
| SCHEMBL10795807 | 0.81 | LMNA (0.41) | MAPTGPBAR1MLYCDALDH1A1LMNA | |
| SCHEMBL11074226 | 0.80 | TLR7 (0.40) | TLR7MEN1KMT2ATLR8GPBAR1 | |
| SCHEMBL11074223 | 0.80 | TLR7 (0.40) | TLR7MEN1KMT2ATLR8GPBAR1 | |
| SCHEMBL10795425 | 0.79 | TDP1 (0.51) | TLR7MEN1USP2MAPTALOX15 | |
| SCHEMBL4908017 | 0.78 | GPBAR1 (0.48) | TLR7MEN1KMT2AGPBAR1ALDH1A1 | |
| SCHEMBL11372591 | 0.78 | KMT2A (0.41) | TLR7MEN1MAPTKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32418-E | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1987-05-12 | — | — | US | claimed |
| US-4170657-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1979-10-09 | — | — | US | claimed |
| US-4431667-A | Imino ethers useful for controlling insect and arachnoid pests | THE UPJOHN COMPANY (US) | 1984-02-14 | — | — | US | disclosed |