Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PPIA | P62937 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.35 |
| ▸ | RAF1 | P04049 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10798009 | 0.88 | TDP1 (0.52) | LMNAGAATDP1MAPTALDH1A1 | |
| SCHEMBL10798028 | 0.83 | TLR7 (0.44) | LMNATDP1MAPTALDH1A1MLYCD | |
| SCHEMBL10794817 | 0.81 | TLR7 (0.44) | LMNAMAPTALDH1A1MLYCDGPBAR1 | |
| SCHEMBL11077927 | 0.77 | LMNA (0.34) | LMNAGAAMAPTPOLQCTSS | |
| SCHEMBL11077924 | 0.77 | LMNA (0.34) | LMNAGAAMAPTPOLQCTSS | |
| SCHEMBL10795802 | 0.77 | TDP1 (0.43) | LMNAGAATDP1PPIAMAPT | |
| SCHEMBL11079534 | 0.76 | POLQ (0.36) | LMNATDP1MAPTALDH1A1MLYCD | |
| SCHEMBL11079529 | 0.76 | POLQ (0.36) | LMNATDP1MAPTALDH1A1MLYCD | |
| SCHEMBL437155 | 0.75 | TDP1 (0.52) | GAATDP1ALDH1A1RECQL | |
| SCHEMBL4909640 | 0.71 | TLR7 (0.43) | MAPTALDH1A1MLYCDGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32418-E | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1987-05-12 | — | — | US | claimed |
| US-4170657-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1979-10-09 | — | — | US | claimed |
| US-4431667-A | Imino ethers useful for controlling insect and arachnoid pests | THE UPJOHN COMPANY (US) | 1984-02-14 | — | — | US | disclosed |