Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10792247 | 0.86 | CYP11B1 (0.39) | P2RX7SMN1; SMN2ALDH1A1PHF8LMNA | |
| SCHEMBL10792191 | 0.83 | CYP11B1 (0.39) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL10791602 | 0.81 | PHF8 (0.44) | P2RX7KDM4CRAB9AGAASMN1; SMN2 | |
| SCHEMBL10792293 | 0.80 | KDM4C (0.39) | KDM4CNPC1RAB9AACP1GAA | |
| SCHEMBL10792639 | 0.76 | ACP1 (0.40) | ACP1GAAALDH1A1PHF8LMNA | |
| SCHEMBL10791998 | 0.75 | CYP11B1 (0.51) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10791376 | 0.75 | TSHR (0.42) | P2RX7SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10795248 | 0.75 | PHF8 (0.50) | KDM4CRAB9ASMN1; SMN2PHF8LMNA | |
| SCHEMBL11049916 | 0.74 | HPGDS (0.43) | KDM4CNPC1RAB9ASMN1; SMN2PHF8 | |
| SCHEMBL2200116 | 0.74 | HPGDS (0.40) | P2RX7KDM4CNPC1RAB9APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32400-E | Substituted imidazole derivatives and their use as anti-thrombosis agents | FARMOS YHTYMA OY (FI) | 1987-04-14 | — | — | US | disclosed |
| US-4514412-A | HYPOTENSIVES, BETA BLOCKERS | FARMOS YHTYMA OY (FI) | 1985-04-30 | — | — | US | disclosed |
| EP-0058047-B1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos-Yhtyma Oy (FI) | 1984-11-07 | — | — | EP | disclosed |
| EP-0058047-A1 | Substituted imidazole derivatives and their preparation and use | Farmos-Yhtyma Oy (FI) | 1982-08-18 | — | — | EP | disclosed |