Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | WRN | Q14191 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13603985 | 0.77 | MGLL (0.33) | MGLLGSK3AGSK3BALDH1A1BLM | |
| SCHEMBL819470 | 0.69 | — | — | |
| SCHEMBL10666060 | 0.67 | MGLL (0.42) | MGLLGSK3AGSK3BALDH1A1BLM | |
| SCHEMBL7139394 | 0.67 | MGLL (0.42) | MGLLGSK3AGSK3BALDH1A1BLM | |
| SCHEMBL9576348 | 0.65 | MGLL (0.36) | MGLLGSK3AGSK3BALDH1A1BLM | |
| SCHEMBL12735283 | 0.63 | MGLL (0.39) | MGLLGSK3AGSK3BALDH1A1BLM | |
| SCHEMBL6690331 | 0.63 | MGLL (0.39) | MGLLGSK3AGSK3BALDH1A1BLM | |
| SCHEMBL3482758 | 0.63 | MGLL (0.45) | MGLLGSK3AGSK3BALDH1A1BLM | |
| SCHEMBL2493031 | 0.63 | — | — | |
| SCHEMBL3482689 | 0.62 | MGLL (0.38) | MGLLGSK3AGSK3BALDH1A1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32504-E | Room temperature stable organopolysiloxane compositions | WACKER-CHEMIE GMBH (DE) | 1987-09-15 | — | — | US | disclosed |
| EP-0123321-B1 | PROCESS FOR RETICULATING ORGANOPOLYSILOXANE COMPOSITIONS | Wacker-Chemie GmbH (DE) | 1987-03-25 | — | — | EP | disclosed |
| US-4530989-A | Blend containing maleimide and a maleic acid derivative; delay or prevent crosslinking | WACKER-CHEMIE GMBH (DE) | 1985-07-23 | — | — | US | disclosed |
| EP-0123321-A2 | Process for reticulating organopolysiloxane compositions | Wacker-Chemie GmbH (DE) | 1984-10-31 | — | — | EP | disclosed |