⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10666060 | 0.73 | MGLL (0.42) | — | |
| SCHEMBL7139394 | 0.73 | MGLL (0.42) | — | |
| SCHEMBL14699650 | 0.69 | MGLL (0.33) | — | |
| SCHEMBL15892773 | 0.69 | MGLL (0.35) | — | |
| SCHEMBL819470 | 0.69 | — | — | |
| SCHEMBL6022398 | 0.67 | NQO1 (0.34) | — | |
| SCHEMBL712983 | 0.67 | MGLL (0.36) | — | |
| SCHEMBL5071662 | 0.65 | ALDH1A1 (0.35) | — | |
| SCHEMBL317848 | 0.65 | MGLL (0.35) | — | |
| SCHEMBL9728517 | 0.65 | MGLL (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116515950-A | Antigen-coupled hybridization reagents | 赛尔伊迪克斯公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-109716130-B | Antigen-coupled hybridization reagents | 赛尔伊迪克斯公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-109265512-B | Preparation method of protein conjugate based on pyridine dicarbaldehyde | 清华大学 | 2021-06-11 | — | — | CN | disclosed |
| US-8030459-B2 | Oxime conjugates and methods for their formation and use | THE GENERAL HOSPITAL CORPORATION (US) | 2011-10-04 | — | — | US | disclosed |
| US-20060058513-A1 | Oxime conjugates and methods for their formation and use | ENERGY, UNITED STATES DEPARTMENT OF | 2006-03-16 | — | — | US | disclosed |
| EP-1534269-A1 | OXIME CONJUGATES AND METHODS FOR THEIR FORMATION AND USE | THE GENERAL HOSPITAL CORPORATION (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004009082-A1 | OXIME CONJUGATES AND METHODS FOR THEIR FORMATION AND USE | THE GENERAL HOSPITAL CORPORATION (US) | 2004-01-29 | — | — | WO | disclosed |