Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.42 |
| ▸ | PPARA | Q07869 | 11/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.42 |
| ▸ | PTGES | O14684 | 5/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268024 | 0.79 | NR1I2 (0.49) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9856427 | 0.79 | PPARG (0.38) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL10789684 | 0.79 | LTA4H (0.44) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL14119420 | 0.78 | MEN1 (0.57) | ALDH1A1KDM4ELMNAPOLBRAB9A | |
| SCHEMBL4872642 | 0.78 | ALDH1A1 (0.54) | S1PR1ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL11280179 | 0.77 | SMN1; SMN2 (0.46) | S1PR1ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL12781078 | 0.77 | CA12 (0.56) | S1PR1ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL5583900 | 0.77 | ALDH1A1 (0.53) | S1PR1ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL9856294 | 0.76 | PPARG (0.39) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9856269 | 0.76 | TAAR1 (0.44) | PPARGPPARAALOX5PTGESSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4697033-A | INSECTICIDES | SANDOZ LTD. (CH) | 1987-09-29 | — | — | US | disclosed |