Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.39 |
| ▸ | PPARA | Q07869 | 10/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.39 |
| ▸ | PTGES | O14684 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10789684 | 0.86 | LTA4H (0.44) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9268024 | 0.83 | NR1I2 (0.49) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9268482 | 0.83 | PPARG (0.42) | PPARGPPARAALOX5PTGESTDP1 | |
| SCHEMBL9856269 | 0.83 | TAAR1 (0.44) | PPARGPPARAALOX5PTGESTDP1 | |
| SCHEMBL9262825 | 0.78 | NPC1 (0.40) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL23295252 | 0.78 | NQO1 (0.34) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9856427 | 0.77 | PPARG (0.38) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9856458 | 0.77 | MTNR1A (0.43) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL10394254 | 0.77 | MTNR1A (0.38) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9856170 | 0.77 | CA12 (0.44) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |