Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.38 |
| ▸ | PPARA | Q07869 | 12/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 10/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 7/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10789684 | 0.80 | LTA4H (0.44) | PPARGPPARAALOX5PTGESCA12 | |
| SCHEMBL10791820 | 0.79 | — | — | |
| SCHEMBL10795293 | 0.79 | PPARG (0.42) | PPARGPPARAALOX5PTGESCA12 | |
| SCHEMBL10795412 | 0.78 | PTPN1 (0.40) | PTPN1CA12CA1CA2CA7 | |
| SCHEMBL9268482 | 0.77 | PPARG (0.42) | PPARGPPARAALOX5PTGES | |
| SCHEMBL9856294 | 0.77 | PPARG (0.39) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9856269 | 0.77 | TAAR1 (0.44) | PPARGPPARAALOX5PTGES | |
| SCHEMBL9268024 | 0.77 | NR1I2 (0.49) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9262825 | 0.75 | NPC1 (0.40) | PPARGPPARAALOX5PTGESNPC1 | |
| SCHEMBL9273996 | 0.75 | ALDH1A1 (0.48) | PTPN1TSHRNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |