Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10797902 | 0.91 | TDP1 (0.45) | TDP1TYK2NPC1KDM4EALDH1A1 | |
| SCHEMBL10798511 | 0.87 | ATM (0.49) | TDP1TYK2NPC1KDM4EALDH1A1 | |
| SCHEMBL11339687 | 0.81 | GAA (0.53) | TDP1TYK2NPC1KDM4EALDH1A1 | |
| SCHEMBL10796005 | 0.81 | TDP1 (0.61) | TDP1TYK2NPC1KDM4EALDH1A1 | |
| SCHEMBL8660829 | 0.80 | ATM (0.47) | TDP1TYK2NPC1KDM4EALDH1A1 | |
| SCHEMBL11074638 | 0.79 | RAB9A (0.37) | TYK2NPC1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL11074639 | 0.79 | RAB9A (0.37) | TYK2NPC1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL10799709 | 0.79 | ATM (0.46) | TDP1TYK2NPC1KDM4EALDH1A1 | |
| SCHEMBL9736809 | 0.78 | PTGS2 (0.53) | TYK2NPC1KDM4EMAPK1TAS1R3 | |
| SCHEMBL7599768 | 0.78 | EPHX2 (0.58) | TDP1TYK2NPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32418-E | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1987-05-12 | — | — | US | claimed |
| US-4170657-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1979-10-09 | — | — | US | claimed |
| US-4431667-A | Imino ethers useful for controlling insect and arachnoid pests | THE UPJOHN COMPANY (US) | 1984-02-14 | — | — | US | disclosed |