Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11351845 | 0.85 | KMT2A (0.48) | PTGS2MAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL9348852 | 0.84 | KMT2A (0.46) | MAPTKMT2AMEN1CYP3A4RAB9A | |
| SCHEMBL9352624 | 0.84 | NPC1 (0.50) | MAPTKMT2AMEN1CYP3A4CYP1A2 | |
| Dichlorbenzuron SCHEMBL3663126 | 0.83 | CNR1 (0.54) | KMT2AMEN1CYP3A4RAB9ANPC1 | |
| SCHEMBL9348629 | 0.82 | NPC1 (0.48) | MAPTKMT2AMEN1CYP3A4RAB9A | |
| SCHEMBL9702804 | 0.82 | MAPT (0.59) | MAPTKMT2AMEN1CYP3A4CYP1A2 | |
| SCHEMBL9737557 | 0.82 | MAPT (0.49) | MAPTKMT2AMEN1CYP3A4CYP1A2 | |
| SCHEMBL11244841 | 0.82 | MAOA (0.51) | MAPTKMT2AMEN1CYP3A4RAB9A | |
| SCHEMBL7605864 | 0.82 | KMT2A (0.61) | MAPTKMT2AMEN1CYP3A4RAB9A | |
| SCHEMBL7603611 | 0.81 | RAB9A (0.50) | MAPTKMT2AMEN1CYP3A4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142064-A | Larvicides has benzoyl or thiobenzoyl group | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-08-25 | — | — | US | claimed |