Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10798009 | 0.87 | TDP1 (0.52) | TDP1RAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL515847 | 0.80 | TDP1 (0.80) | TDP1RAB9AALDH1A1HTTNPC1 | |
| SCHEMBL10798005 | 0.76 | TDP1 (0.57) | TDP1RAB9AALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL10795807 | 0.75 | LMNA (0.41) | TDP1ALDH1A1GAARECQL | |
| SCHEMBL1901350 | 0.75 | TDP1 (0.53) | TDP1RAB9AALDH1A1HTTNPC1 | |
| SCHEMBL10798028 | 0.75 | TLR7 (0.44) | TDP1ALDH1A1NPC1KDM4ETYK2 | |
| SCHEMBL10592345 | 0.73 | TDP1 (0.59) | TDP1RAB9AALDH1A1NPC1KDM4E | |
| SCHEMBL1567759 | 0.73 | TDP1 (0.64) | TDP1RAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL7832960 | 0.72 | TDP1 (0.63) | TDP1RAB9AALDH1A1NPC1RORC | |
| SCHEMBL11080519 | 0.72 | TDP1 (0.40) | TDP1RAB9AALDH1A1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101772-B2 | Fungicidal active substance combinations containing trifloxystrobin | BAYER CROPSCIENCE AG (DE) | 2012-01-24 | — | — | US | disclosed |
| US-20050009703-A1 | Synergistic mixture of trifloxystrobin and imidacloprid | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009703-A1 | Synergistic mixture of trifloxystrobin and imidacloprid | THOP1, TH, ERG28 | TDP1 3436/4885RAB9A 3770/4885ALDH1A1 4034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.