SCHEMBL10796264

SCHEMBL10796264

Nc1cc2cccc(O)c2cc1C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.67
GRIN2A Q12879 1/20 0.67
GRIN2B Q13224 1/20 0.67
GRIN2C Q14957 1/20 0.67
IDO1 P14902 1/20 0.62
CASP7 P55210 2/20 0.50
G6PD P11413 1/20 0.50
CASP6 P55212 1/20 0.50
PLAU P00749 1/20 0.49
CTDSP1 Q9GZU7 1/20 0.49
MMP2 P08253 1/20 0.46
MAOA P21397 1/20 0.45
PTPN1 P18031 2/20 0.45
TBK1 Q9UHD2 1/20 0.43
KDM4E B2RXH2 4/20 0.43
KMT2A Q03164 3/20 0.43
NR4A1 P22736 1/20 0.43
NR4A2 P43354 1/20 0.43
NR4A3 Q92570 1/20 0.43
GFER P55789 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10353592 0.85 GRIN2D (0.82) GRIN2DGRIN2AGRIN2BGRIN2CIDO1
SCHEMBL3391564 0.84 GRIN2D (0.86) GRIN2DGRIN2AGRIN2BGRIN2CCASP7
SCHEMBL7996107 0.83 IDO1 (0.68) GRIN2DGRIN2AGRIN2BGRIN2CIDO1
Anthranilic Acid SCHEMBL7177136 0.81 GRIN2D (0.59) GRIN2DGRIN2AGRIN2BGRIN2CIDO1
SCHEMBL29620342 0.80 GRIN2D (1.00) GRIN2DGRIN2AGRIN2BGRIN2CCASP7
SCHEMBL10824259 0.80 GRIN2D (0.73) GRIN2DGRIN2AGRIN2BGRIN2CCASP7
SCHEMBL214909 0.80 GRIN2D (1.00) GRIN2DGRIN2AGRIN2BGRIN2CCASP7
Questiomycin B SCHEMBL8006530 0.79 IDO1 (0.79) GRIN2DGRIN2AGRIN2BGRIN2CIDO1
SCHEMBL8534112 0.79 PLAU (0.61) GRIN2DGRIN2AGRIN2BGRIN2CIDO1
SCHEMBL987747 0.79 IDO1 (0.67) GRIN2DGRIN2AGRIN2BGRIN2CIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4673631-A OF AN AMINO ACID COMPOUND CANON KABUSHIKI KAISHA (JP) 1987-06-16 US disclosed