SCHEMBL10797201

SCHEMBL10797201

O=C(O)c1c(CC=CO)ccc2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.47
ALDH1A1 P00352 2/20 0.47
GLA P06280 2/20 0.47
HPGD P15428 2/20 0.47
HSD17B10 Q99714 2/20 0.47
MEN1 O00255 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C19 P33261 1/20 0.47
KMT2A Q03164 1/20 0.47
METAP2 P50579 2/20 0.41
METAP1 P53582 1/20 0.41
WDR5 P61964 1/20 0.41
LDHA P00338 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
NR4A1 P22736 1/20 0.40
NR4A2 P43354 1/20 0.40
NR4A3 Q92570 1/20 0.40
ABCG2 Q9UNQ0 1/20 0.39
CDC25B P30305 1/20 0.39
ME2 P23368 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL366864 0.86 MTNR1A (0.37) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL7378331 0.86 KDM4E (0.46) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL28051080 0.83 MEN1 (0.54) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL17530757 0.83 KDM4E (0.49) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL487677 0.83 KDM4E (0.49) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL4591157 0.81 MEN1 (0.51) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL29913819 0.80 KDM4E (0.57) KDM4EALDH1A1GLAHPGDHSD17B10
Bicarbonate SCHEMBL18917593 0.79 TDP1 (0.56) KDM4EHPGDMEN1CYP1A2CYP2C19
SCHEMBL897607 0.78 KDM4E (0.55) KDM4EALDH1A1GLAHPGDHSD17B10
Ammonia Solution, Strong SCHEMBL7720474 0.77 KDM4E (0.53) KDM4EALDH1A1GLAHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0076998-B1 METHOD FOR PREPARING CONDENSATION POLYMERS BY EMULSION POLYMERIZATION DOW CORNING CORPORATION (US) 1987-04-15 EP disclosed
EP-0076998-A1 Method for preparing condensation polymers by emulsion polymerization DOW CORNING CORPORATION (US) 1983-04-20 EP disclosed
US-4355154-A Method for preparing condensation polymers by emulsion polymerization DOW CORNING CORPORATION (US) 1982-10-19 US disclosed