Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1072568 | 0.86 | KDM4E (0.45) | KDM4ENPC1ALDH1A1LMNATSHR | |
| Adamantane SCHEMBL28164719 | 0.75 | ACHE (0.54) | KDM4ENPC1ALDH1A1LMNATSHR | |
| Carbamic Acid SCHEMBL15015728 | 0.75 | TSHR (0.46) | KDM4ENPC1ALDH1A1LMNATSHR | |
| SCHEMBL4275734 | 0.72 | KDM4E (0.30) | KDM4EALDH1A1LMNA | |
| SCHEMBL10798452 | 0.72 | KDM4E (0.50) | KDM4ENPC1ALDH1A1LMNATSHR | |
| SCHEMBL14938504 | 0.68 | KDM4E (0.65) | KDM4ENPC1ALDH1A1LMNATSHR | |
| Carbamic Acid SCHEMBL10796501 | 0.68 | TSHR (0.41) | KDM4ENPC1ALDH1A1LMNATSHR | |
| Adamantane SCHEMBL3723679 | 0.66 | ALDH1A1 (0.50) | KDM4ENPC1ALDH1A1LMNATSHR | |
| SCHEMBL8398977 | 0.66 | KDM4E (0.45) | KDM4ENPC1ALDH1A1LMNATSHR | |
| SCHEMBL12765667 | 0.66 | TSHR (0.36) | KDM4ENPC1ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4652680-A | 2-adamantanone oxide carbamate derivatives | PENNWALT CORPORATION (US) | 1987-03-24 | — | — | US | disclosed |
| US-4652680-A | 2-adamantanone oxide carbamate derivatives | PENNWALT CORPORATION (US) | 1987-03-24 | — | — | US | disclosed |
| EP-0191912-A1 | 2-Adamantanone oxime carbamate derivatives | PENNWALT CORPORATION (US) | 1986-08-27 | — | — | EP | disclosed |
| EP-0191912-A1 | 2-Adamantanone oxime carbamate derivatives | PENNWALT CORPORATION (US) | 1986-08-27 | — | — | EP | disclosed |
| EP-0191912-A1 | 2-Adamantanone oxime carbamate derivatives | PENNWALT CORPORATION (US) | 1986-08-27 | — | — | EP | disclosed |