Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adamantane SCHEMBL28164719 | 0.88 | ACHE (0.54) | ALDH1A1LMNAOR51E2TDP1TSHR | |
| Adamantane SCHEMBL14841654 | 0.85 | LMNA (0.57) | ALDH1A1LMNAOR51E2TDP1TSHR | |
| Adamantane SCHEMBL974954 | 0.78 | HSD11B1 (0.48) | LMNATSHRHSD11B1CYP2C9THRB | |
| Adamantane SCHEMBL935449 | 0.78 | HSD11B1 (0.48) | LMNATSHRHSD11B1CYP2C9THRB | |
| Adamantane SCHEMBL851674 | 0.78 | CYP2C9 (0.41) | TSHRHSD11B1CYP2C9EPHX1EPHX2 | |
| Adamantane SCHEMBL3981833 | 0.78 | HSD11B1 (0.48) | LMNATSHRHSD11B1CYP2C9THRB | |
| Adamantane SCHEMBL16735409 | 0.77 | CYP2C9 (0.47) | ALDH1A1LMNATSHRKDM4EHSD11B1 | |
| Adamantane SCHEMBL25171693 | 0.75 | TSHR (0.50) | ALDH1A1LMNATSHRNPC1KDM4E | |
| Adamantane SCHEMBL28005909 | 0.75 | LMNA (0.50) | LMNATSHRHSD11B1CYP2C9EPHX1 | |
| Adamantane SCHEMBL9316202 | 0.75 | HSD11B1 (0.46) | LMNATSHRHSD11B1CYP2C9THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272885-A | Method for preparation of novel adamantane derivative | UNIV BEIJING CHEMICAL | 2016-01-27 | — | — | CN | claimed |
| CN-115745806-B | Recovery process of amantadine hydrochloride tail gas material | 天津民祥药业有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-115745806-A | Recovery process of amantadine hydrochloride tail gas material | 天津民祥药业有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-108349955-A | The analog of adamantyl urea as solvable epoxides enzyme inhibitor | 巴塞罗那大学 | 2018-07-31 | — | — | CN | disclosed |
| CN-105272885-A | Method for preparation of novel adamantane derivative | UNIV BEIJING CHEMICAL | 2016-01-27 | — | — | CN | disclosed |
| WO-2010112946-A1 | ADAMANTANE BISUREA DERIVATIVES, METHOD OF PREPARATION AND APPLICATION IN ANION SENSING | RUDJER BOSKOVIC INSTITUTE (HR) | 2010-10-07 | — | — | WO | disclosed |