Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | TTR | P02766 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | FABP2 | P12104 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10799298 | 0.67 | HPGD (0.45) | TSHRLMNAPTGS2MEN1KMT2A | |
| SCHEMBL10794161 | 0.66 | KCNN4 (0.36) | CLCN2TSHRLMNAPTGS2TTR | |
| SCHEMBL3667462 | 0.65 | TSHR (0.50) | TSHRALDH1A1 | |
| SCHEMBL1143087 | 0.64 | TSHR (0.55) | TSHRALDH1A1LMNA | |
| SCHEMBL10798796 | 0.62 | LMNA (0.36) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL1409623 | 0.62 | TSHR (0.60) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL6049865 | 0.61 | TSHR (0.58) | TSHRALDH1A1LMNA | |
| Iodide SCHEMBL25233686 | 0.60 | TSHR (0.57) | TSHRALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL16447038 | 0.60 | TSHR (0.57) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL3676489 | 0.60 | TSHR (0.44) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088667-B1 | HALOGENATED AROMATIC DIAMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE PREPARATION OF POLYURETHANES | ELF ATOCHEM S.A. (FR) | 1987-04-08 | — | — | EP | claimed |