Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SPR | P35270 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10751687 | 0.90 | KMT2A (0.36) | MAPTKDM4ESPRHTTSMN1; SMN2 | |
| SCHEMBL10808922 | 0.89 | MAPT (0.34) | MAPTKDM4ESPRHTTSMN1; SMN2 | |
| SCHEMBL10754739 | 0.84 | MAPT (0.38) | MAPTKDM4ESPRHTTSMN1; SMN2 | |
| SCHEMBL10680900 | 0.83 | MAPT (0.36) | MAPTKDM4EHTTSMN1; SMN2NR2F2 | |
| SCHEMBL10803143 | 0.80 | L3MBTL1 (0.41) | MAPTKDM4ESPRHTTSMN1; SMN2 | |
| SCHEMBL1324474 | 0.78 | KMT2A (0.52) | MAPTKDM4EHTTSMN1; SMN2NR2F2 | |
| SCHEMBL10751550 | 0.78 | MAPT (0.43) | MAPTKDM4ESPRHTTSMN1; SMN2 | |
| SCHEMBL10751359 | 0.77 | ALDH1A1 (0.46) | MAPTSPRSMN1; SMN2KMT2APOLB | |
| SCHEMBL10752306 | 0.77 | KMT2A (0.51) | MAPTKDM4EHTTSMN1; SMN2NR2F2 | |
| SCHEMBL10752411 | 0.77 | SMN1; SMN2 (0.51) | MAPTKDM4EHTTSMN1; SMN2NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071833-B1 | PROCESS FOR PRODUCING 4-BENZOYLPYRAZOLES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-02-04 | — | — | EP | disclosed |