Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10799987 | 0.82 | FOLH1 (0.46) | CTSLRECQLHPGDFOLH1NPC1 | |
| SCHEMBL10805989 | 0.82 | CTSL (0.66) | ALDH1A1CTSLLMNAACECTRB1 | |
| SCHEMBL10805205 | 0.81 | FOLH1 (0.50) | FOLH1NPC1 | |
| SCHEMBL10801723 | 0.81 | CTSL (0.48) | ALDH1A1CTSLRECQLTDP1HPGD | |
| SCHEMBL6313152 | 0.80 | L3MBTL1 (0.61) | ALDH1A1HSD17B10LMNATDP1HPGD | |
| SCHEMBL3706987 | 0.80 | L3MBTL1 (0.61) | ALDH1A1HSD17B10LMNATDP1HPGD | |
| SCHEMBL28138297 | 0.79 | ACE (0.61) | ALDH1A1CTSLTDP1HPGDACE | |
| SCHEMBL28138300 | 0.79 | ACE (0.61) | ALDH1A1CTSLTDP1HPGDACE | |
| SCHEMBL27967837 | 0.79 | CTSB (0.48) | ALDH1A1 | |
| SCHEMBL10805329 | 0.79 | CTSL (0.43) | ALDH1A1CTSLRECQLHPGDACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0134561-B1 | ALPHA-ALLENIC-ALPHA-AMINO ACIDS | SYNTEX (U.S.A.) INC. (US) | 1987-07-08 | — | — | EP | disclosed |
| EP-0134561-A1 | Alpha-allenic-alpha-amino acids | SYNTEX (U.S.A.) INC. (US) | 1985-03-20 | — | — | EP | disclosed |