Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10805566 | 0.85 | CYP3A4 (0.30) | — | |
| SCHEMBL10801585 | 0.81 | KDM4E (0.30) | NPC1ALDH1A1RAB9A | |
| SCHEMBL7719782 | 0.78 | ALDH1A1 (0.34) | NPC1ALDH1A1CASP3RAB9ASENP8 | |
| SCHEMBL8086579 | 0.77 | MEN1 (0.45) | ALDH1A1RAB9A | |
| SCHEMBL11168353 | 0.75 | TRPA1 (0.35) | ALDH1A1GLAMAPK1 | |
| SCHEMBL10830507 | 0.73 | TSHR (0.36) | ALDH1A1MAPK1RAB9A | |
| SCHEMBL10476775 | 0.73 | MAOA (0.39) | NPC1ALDH1A1RAB9A | |
| SCHEMBL9160477 | 0.73 | MAOA (0.39) | NPC1ALDH1A1RAB9A | |
| SCHEMBL36333 | 0.73 | MAOA (0.39) | NPC1ALDH1A1RAB9A | |
| SCHEMBL1037618 | 0.72 | ALDH1A1 (0.34) | NPC1ALDH1A1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110831-B1 | THIOXANTHONES SUBSTITUTED BY ALPHA-AMINOALKYL GROUPS | CIBA-GEIGY AG (CH) | 1987-03-04 | — | — | EP | disclosed |
| US-4564578-A | PHOTOSENSITIVE EPOXY RESINS | CIBA-GEIGY CORPORATION (US) | 1986-01-14 | — | — | US | disclosed |
| EP-0110831-A1 | Thioxanthones substituted by alpha-aminoalkyl groups | CIBA-GEIGY AG (CH) | 1984-06-13 | — | — | EP | disclosed |