Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23722532 | 0.81 | TGM2 (0.51) | LMNA | |
| SCHEMBL19002557 | 0.79 | L3MBTL1 (0.53) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL30828432 | 0.78 | CRBN (0.56) | POLBMAPTMEN1KMT2AKDM4E | |
| SCHEMBL15408396 | 0.76 | NPC1 (0.63) | MAPTKDM4ESMN1; SMN2HTTMAPK1 | |
| SCHEMBL3559931 | 0.75 | ALDH1A1 (0.50) | MAPTALDH1A1L3MBTL1LMNAHPGD | |
| SCHEMBL2883318 | 0.74 | ADRB1 (0.47) | POLBMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL2199529 | 0.74 | KMT2A (0.41) | POLBMAPTMEN1KMT2AKDM4E | |
| SCHEMBL532005 | 0.74 | KMT2A (0.73) | POLBMAPTMEN1KMT2AKDM4E | |
| SCHEMBL1677937 | 0.74 | GAA (0.64) | POLBMAPTMEN1KMT2AKDM4E | |
| SCHEMBL10022670 | 0.73 | ALDH1A1 (0.57) | POLBMAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4634713-A | ADRENERGIC BLOCKING AGENTS | CIBA-GEIGY CORPORATION (US) | 1987-01-06 | — | — | US | disclosed |
| EP-0096006-A2 | 3-(Ureidocyclohexylamino)-propane-1,2-diol derivatives, process for their preparation, pharmaceutical preparations containing these compounds and their therapeutical use | CIBA-GEIGY AG (CH) | 1983-12-07 | — | — | EP | disclosed |