Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10801519 | 0.94 | KMT2A (0.46) | MEN1KMT2AVCAM1ALDH1A1ALDH3A1 | |
| SCHEMBL10806658 | 0.82 | ALDH1A1 (0.52) | MEN1KMT2AVCAM1ALDH1A1ALDH3A1 | |
| SCHEMBL10803999 | 0.81 | ALDH1A1 (0.49) | MEN1KMT2AVCAM1ALDH1A1ALDH3A1 | |
| SCHEMBL7320813 | 0.81 | PRSS1 (0.53) | MEN1KMT2AVCAM1ALDH1A1MAPT | |
| SCHEMBL11829181 | 0.80 | KMT2A (0.42) | MEN1KMT2AVCAM1ALDH1A1MAPT | |
| SCHEMBL29246356 | 0.80 | SMN1; SMN2 (0.41) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL10805869 | 0.80 | ALDH1A1 (0.53) | MEN1KMT2AVCAM1ALDH1A1ALDH3A1 | |
| SCHEMBL11089907 | 0.80 | MEN1 (0.42) | MEN1KMT2AVCAM1ALDH1A1MAPT | |
| SCHEMBL10805882 | 0.77 | BCL9 (0.49) | MEN1KMT2AALDH1A1ALDH3A1MAPT | |
| SCHEMBL10801357 | 0.77 | ALDH1A1 (0.45) | MEN1KMT2AVCAM1ALDH1A1ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063101-B1 | NITROARYL-ALKYL-SULFONE DERIVATIVES AS GAMETOCIDES | CIBA-GEIGY AG (CH) | 1987-04-01 | — | — | EP | disclosed |
| EP-0063101-A1 | Nitroaryl-alkyl-sulfone derivatives as gametocides | CIBA-GEIGY AG (CH) | 1982-10-20 | — | — | EP | disclosed |