Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10804963 | 0.94 | MEN1 (0.48) | KMT2AMEN1VCAM1MAPTLMNA | |
| SCHEMBL28448328 | 0.82 | ALDH1A1 (0.52) | KMT2AMEN1MAPTL3MBTL1LMNA | |
| SCHEMBL10803968 | 0.81 | ALDH1A1 (0.45) | KMT2AMEN1VCAM1MAPTL3MBTL1 | |
| SCHEMBL10806658 | 0.79 | ALDH1A1 (0.52) | KMT2AMEN1VCAM1MAPTLMNA | |
| SCHEMBL7622572 | 0.79 | CLK1 (0.45) | KMT2AMEN1MAPTL3MBTL1LMNA | |
| SCHEMBL8315096 | 0.78 | MAPT (0.51) | KMT2AMEN1MAPTL3MBTL1LMNA | |
| SCHEMBL28832071 | 0.78 | NPBWR1 (0.54) | KMT2AMEN1VCAM1MAPTL3MBTL1 | |
| SCHEMBL10805869 | 0.77 | ALDH1A1 (0.53) | KMT2AMEN1VCAM1MAPTLMNA | |
| SCHEMBL10803999 | 0.76 | ALDH1A1 (0.49) | KMT2AMEN1VCAM1MAPTL3MBTL1 | |
| SCHEMBL7320813 | 0.75 | PRSS1 (0.53) | KMT2AMEN1VCAM1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063101-B1 | NITROARYL-ALKYL-SULFONE DERIVATIVES AS GAMETOCIDES | CIBA-GEIGY AG (CH) | 1987-04-01 | — | — | EP | claimed |
| EP-0063101-A1 | Nitroaryl-alkyl-sulfone derivatives as gametocides | CIBA-GEIGY AG (CH) | 1982-10-20 | — | — | EP | claimed |
| EP-0063101-B1 | NITROARYL-ALKYL-SULFONE DERIVATIVES AS GAMETOCIDES | CIBA-GEIGY AG (CH) | 1987-04-01 | — | — | EP | disclosed |
| EP-0063101-A1 | Nitroaryl-alkyl-sulfone derivatives as gametocides | CIBA-GEIGY AG (CH) | 1982-10-20 | — | — | EP | disclosed |