Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | PTAFR | P25105 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 3/20 | 0.39 |
| ▸ | P2RY10 | O00398 | 7/20 | 0.39 |
| ▸ | GPR34 | Q9UPC5 | 4/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GPR174 | Q9BXC1 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10809708 | 0.96 | ADRA1D (0.45) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL10806858 | 0.92 | CETP (0.41) | CETPP2RY10GPR34THRATHRB | |
| SCHEMBL10806131 | 0.87 | CETP (0.40) | CETPP2RY10GPR34THRATHRB | |
| SCHEMBL10807984 | 0.83 | S1PR1 (0.51) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL10808732 | 0.83 | S1PR1 (0.51) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL10804674 | 0.82 | PPARA (0.47) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL10806787 | 0.81 | LTB4R (0.39) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL10811640 | 0.81 | LTB4R (0.39) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL10807294 | 0.80 | ADRA1D (0.39) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL10809418 | 0.80 | ADRA1D (0.41) | ADRA1DPTAFRHTR1DHTR2CADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4640913-A | Phosphocholine derivatives having antihypertensive action | AMERICAN CYANAMID COMPANY (US) | 1987-02-03 | — | — | US | disclosed |