Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 12/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92986 | 0.85 | LMNA (0.59) | LMNAGAAKMT2ALDHAALDH1A1 | |
| SCHEMBL9264609 | 0.82 | LMNA (0.56) | LMNAGAAKMT2ALDHAALDH1A1 | |
| SCHEMBL9263666 | 0.82 | LMNA (0.56) | LMNAGAAKMT2ALDHAALDH1A1 | |
| SCHEMBL1129788 | 0.78 | LMNA (0.63) | LMNAGAAKMT2ALDHAALDH1A1 | |
| SCHEMBL20446813 | 0.77 | LMNA (0.55) | LMNAGAAKMT2ALDHAALDH1A1 | |
| SCHEMBL10808372 | 0.73 | LMNA (0.44) | LMNAGAAKMT2ALDHAALDH1A1 | |
| SCHEMBL29101546 | 0.73 | SIGMAR1 (0.36) | LMNAGAAKMT2ASIGMAR1KCNA3 | |
| SCHEMBL2466435 | 0.73 | LMNA (0.56) | LMNAGAAKMT2ALDHAALDH1A1 | |
| SCHEMBL21261241 | 0.72 | LMNA (0.56) | LMNAGAAKMT2ALDHAALDH1A1 | |
| SCHEMBL31447811 | 0.72 | LMNA (0.60) | LMNAGAAKMT2ALDHAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |