Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | PTGES | O14684 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240864 | 0.90 | NPSR1 (0.64) | NPSR1PTGESMEN1KMT2AMAPT | |
| SCHEMBL11719116 | 0.88 | NPSR1 (0.57) | NPSR1PTGESMEN1KMT2AMAPT | |
| SCHEMBL11240284 | 0.81 | PTGES (0.57) | NPSR1PTGESMAPTLMNAL3MBTL1 | |
| SCHEMBL10812182 | 0.80 | NPSR1 (0.54) | NPSR1PTGESMEN1KMT2AMAPT | |
| SCHEMBL10809881 | 0.80 | NPSR1 (0.54) | NPSR1MEN1KMT2AMAPTPOLB | |
| SCHEMBL10808538 | 0.80 | NPSR1 (0.79) | NPSR1PTGESMEN1KMT2AMAPT | |
| SCHEMBL10887189 | 0.78 | NPSR1 (0.52) | NPSR1MEN1KMT2AMAPTPOLB | |
| SCHEMBL10508211 | 0.77 | ALDH1A1 (0.60) | NPSR1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL21852751 | 0.74 | ALDH1A1 (0.67) | NPSR1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL25440088 | 0.74 | MAPT (0.58) | PTGESMEN1KMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077983-B1 | TRIAZINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-04-29 | — | — | EP | disclosed |
| US-4616014-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-07 | — | — | US | disclosed |
| EP-0077983-A1 | Triazine derivatives, processes for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-04 | — | — | EP | disclosed |