Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11477773 | 0.94 | NPSR1 (0.58) | PTGESMAPTNPSR1LMNANPC1 | |
| SCHEMBL11240864 | 0.90 | NPSR1 (0.64) | PTGESMAPTNPSR1PTGS2LMNA | |
| SCHEMBL11719116 | 0.84 | NPSR1 (0.57) | PTGESMAPTNPSR1PTGS2NPC1 | |
| SCHEMBL11469387 | 0.84 | LMNA (0.53) | PTGESMAPTPTGS2LMNACACNA2D1 | |
| SCHEMBL11232062 | 0.83 | NPSR1 (0.55) | PTGESMAPTNPSR1LMNANPC1 | |
| SCHEMBL11476250 | 0.81 | MAPT (0.59) | PTGESMAPTPTGS2LMNANPC1 | |
| SCHEMBL10808164 | 0.81 | NPSR1 (0.51) | PTGESMAPTNPSR1PTGS2LMNA | |
| SCHEMBL11247332 | 0.80 | CACNA2D1 (0.51) | PTGESMAPTNPSR1LMNANPC1 | |
| SCHEMBL11860981 | 0.80 | CACNA2D1 (0.51) | PTGESMAPTNPSR1PTGS2LMNA | |
| SCHEMBL11245330 | 0.80 | CACNA2D1 (0.51) | PTGESMAPTNPSR1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318911-A | 5,6-Diaryl-1,2,4-triazines as topical antithrombotic agents | ELI LILLY AND COMPANY (US) | 1982-03-09 | — | — | US | disclosed |