Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | PTGES | O14684 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240864 | 0.94 | NPSR1 (0.64) | NPSR1PTGESKMT2ANPC1RAB9A | |
| SCHEMBL10812615 | 0.89 | NPSR1 (0.70) | NPSR1KMT2ANPC1RAB9APTGS2 | |
| SCHEMBL10808164 | 0.88 | NPSR1 (0.51) | NPSR1PTGESKMT2ANPC1RAB9A | |
| SCHEMBL11240284 | 0.84 | PTGES (0.57) | NPSR1PTGESNPC1RAB9APTGS2 | |
| SCHEMBL2501529 | 0.83 | NPSR1 (0.83) | NPSR1PTGESKMT2APOLBGAA | |
| SCHEMBL2513419 | 0.78 | NPSR1 (0.64) | NPSR1KMT2AMEN1POLBGAA | |
| SCHEMBL11243005 | 0.77 | NPSR1 (0.58) | NPSR1PTGESKMT2AMEN1POLB | |
| SCHEMBL11231108 | 0.77 | PTGES (0.71) | PTGESNPC1RAB9APTGS2GAA | |
| SCHEMBL11230698 | 0.77 | PTGES (0.56) | NPSR1PTGESKMT2ANPC1RAB9A | |
| SCHEMBL11477773 | 0.77 | NPSR1 (0.58) | NPSR1PTGESNPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018923-A | 5,6-Diaryl-1,2,4-triazines as topically-active anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-4013654-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1977-03-22 | — | — | US | disclosed |