Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10808370 | 1.00 | DRD2 (0.33) | DRD2MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL10377663 | 0.82 | RECQL (0.43) | MAPTKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL10377662 | 0.82 | RECQL (0.43) | MAPTKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL10377561 | 0.81 | ALDH1A1 (0.40) | MAPTKDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL10377563 | 0.81 | ALDH1A1 (0.40) | MAPTKDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL10377661 | 0.80 | MAPT (0.46) | MAPTKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL10377359 | 0.80 | CYP1A2 (0.46) | MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL10377660 | 0.80 | MAPT (0.46) | MAPTKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL10378505 | 0.80 | LMNA (0.46) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL10377357 | 0.80 | CYP1A2 (0.46) | MEN1CYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0096890-B1 | OXAZOLEACETIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND COMPOSITIONS CONTAINING SAID DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 1987-11-25 | — | — | EP | disclosed |
| EP-0101023-B1 | PROCESS FOR PREPARING 2-CARBAMOYLOXYALKYL-1,4-DIHYDROPYRIDINE DERIVATIVES AND INTERMEDIATES USEFUL FOR THE PROCESS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1987-07-29 | — | — | EP | disclosed |
| US-4650806-A | Cardiotonic 5-(heterylcarbonyl)-pyridones | STERLING DRUG INC. (US) | 1987-03-17 | — | — | US | disclosed |
| EP-0191298-A2 | 1,6 -Naphthyridin-2(1H) - ones useful as cardiotonics and preparation thereof | STERLING DRUG INC. (US) | 1986-08-20 | — | — | EP | disclosed |
| US-4602027-A | HYPOGLYCEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-07-22 | — | — | US | disclosed |
| US-4567186-A | 5-Heteryl-1,6-naphthyridin-2(1H)-ones, cardiotonic use thereof and intermediates therefor | STERLING DRUG INC. (US) | 1986-01-28 | — | — | US | disclosed |