Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10806787 | 1.00 | LTB4R (0.39) | LTB4RLTB4R2THRATHRBADRA1D | |
| SCHEMBL10807294 | 0.97 | ADRA1D (0.39) | LTB4RLTB4R2THRATHRBADRA1D | |
| SCHEMBL10809418 | 0.95 | ADRA1D (0.41) | LTB4RLTB4R2THRATHRBADRA1D | |
| SCHEMBL10811385 | 0.95 | ADRA1D (0.41) | LTB4RLTB4R2THRATHRBADRA1D | |
| SCHEMBL10810929 | 0.92 | LTB4R (0.38) | LTB4RLTB4R2THRATHRBPPARA | |
| SCHEMBL10808544 | 0.92 | LTB4R (0.38) | LTB4RLTB4R2THRATHRBPPARA | |
| SCHEMBL10803365 | 0.87 | THRA (0.39) | LTB4RLTB4R2THRATHRBADRB2 | |
| SCHEMBL10804028 | 0.87 | THRA (0.39) | LTB4RLTB4R2THRATHRBADRB2 | |
| SCHEMBL10803725 | 0.87 | THRA (0.39) | LTB4RLTB4R2THRATHRBPPARA | |
| SCHEMBL10806556 | 0.87 | THRA (0.39) | LTB4RLTB4R2THRATHRBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4640913-A | Phosphocholine derivatives having antihypertensive action | AMERICAN CYANAMID COMPANY (US) | 1987-02-03 | — | — | US | disclosed |