Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.63 |
| ▸ | XBP1 | P17861 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10812098 | 0.85 | ALDH1A1 (0.47) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL10814864 | 0.83 | MAPT (0.60) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL2887406 | 0.78 | RAB9A (0.71) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL4187625 | 0.78 | SMN1; SMN2 (0.71) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL4675793 | 0.78 | RAB9A (0.71) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL11582931 | 0.78 | SMN1; SMN2 (0.71) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL4743412 | 0.77 | RAB9A (1.00) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL1462668 | 0.76 | RAB9A (0.62) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL2894611 | 0.74 | RAB9A (0.69) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL2895263 | 0.74 | ALDH1A1 (0.69) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0102510-B1 | SUBSTITUTED 4-FLUOROPYRIDAZ-6-ONES | BASF Aktiengesellschaft (DE) | 1987-10-07 | — | — | EP | disclosed |
| EP-0102510-A1 | Substituted 4-fluoropyridaz-6-ones | BASF Aktiengesellschaft (DE) | 1984-03-14 | — | — | EP | disclosed |