Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.69 |
| ▸ | RAB9A | P51151 | 5/20 | 0.69 |
| ▸ | NPC1 | O15118 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | HTT | P42858 | 4/20 | 0.69 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.69 |
| ▸ | XBP1 | P17861 | 2/20 | 0.69 |
| ▸ | NPBWR1 | P48145 | 13/20 | 0.65 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.61 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3028836 | 0.84 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2NPSR1RAB9ANPC1 | |
| SCHEMBL13290336 | 0.81 | RAB9A (0.60) | ALDH1A1SMN1; SMN2NPSR1RAB9ANPC1 | |
| SCHEMBL11582931 | 0.79 | SMN1; SMN2 (0.71) | ALDH1A1SMN1; SMN2NPSR1RAB9ANPC1 | |
| SCHEMBL4675793 | 0.79 | RAB9A (0.71) | ALDH1A1SMN1; SMN2NPSR1RAB9ANPC1 | |
| SCHEMBL2887406 | 0.79 | RAB9A (0.71) | ALDH1A1SMN1; SMN2NPSR1RAB9ANPC1 | |
| SCHEMBL4187625 | 0.79 | SMN1; SMN2 (0.71) | ALDH1A1SMN1; SMN2NPSR1RAB9ANPC1 | |
| SCHEMBL4743412 | 0.78 | RAB9A (1.00) | ALDH1A1SMN1; SMN2NPSR1RAB9ANPC1 | |
| SCHEMBL21526731 | 0.76 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2NPSR1RAB9ANPC1 | |
| SCHEMBL2894611 | 0.75 | RAB9A (0.69) | ALDH1A1SMN1; SMN2NPSR1RAB9ANPC1 | |
| SCHEMBL11728795 | 0.75 | SMN1; SMN2 (1.00) | ALDH1A1SMN1; SMN2NPSR1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732456-B2 | Pyridone derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-06-08 | — | — | US | disclosed |
| US-20070208046-A1 | Pyridone derivative | MSD K.K. (JP) | 2007-09-06 | — | — | US | disclosed |
| EP-1741703-A1 | PYRIDONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208046-A1 | Pyridone derivative | CHRM1, XDH, MTR | ALDH1A1 1714/4885SMN1; SMN2 1299/4885NPSR1 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.