Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.71 |
| ▸ | NPC1 | O15118 | 8/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | HTT | P42858 | 3/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.71 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.71 |
| ▸ | XBP1 | P17861 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 5/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4187625 | 0.83 | SMN1; SMN2 (0.71) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL11582931 | 0.83 | SMN1; SMN2 (0.71) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL4675793 | 0.83 | RAB9A (0.71) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL4743412 | 0.82 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL2894611 | 0.82 | RAB9A (0.69) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL2895263 | 0.79 | ALDH1A1 (0.69) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL10813664 | 0.78 | MAPT (0.63) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL27688150 | 0.77 | NPC1 (0.42) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL4196334 | 0.76 | SMN1; SMN2 (0.60) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL4191812 | 0.76 | RAB9A (0.60) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732456-B2 | Pyridone derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-06-08 | — | — | US | disclosed |
| US-20070208046-A1 | Pyridone derivative | MSD K.K. (JP) | 2007-09-06 | — | — | US | disclosed |
| EP-1741703-A1 | PYRIDONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208046-A1 | Pyridone derivative | CHRM1, XDH, MTR | RAB9A 4619/4885SMN1; SMN2 1299/4885NPC1 4658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.