Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194578 | 0.87 | ALDH1A1 (0.54) | NPC1RAB9AMAPTPOLBMEN1 | |
| SCHEMBL60545 | 0.86 | CYP3A4 (0.51) | NPC1RAB9AMAPTPOLBMEN1 | |
| SCHEMBL19862495 | 0.86 | ALDH1A1 (0.50) | NPC1RAB9AMAPTPOLBMEN1 | |
| SCHEMBL7122940 | 0.85 | NPSR1 (0.56) | NPC1RAB9AMAPTPOLBMEN1 | |
| SCHEMBL10709306 | 0.85 | CES2 (0.50) | NPC1RAB9AMAPTPOLBMEN1 | |
| SCHEMBL10815926 | 0.83 | ALDH1A1 (0.48) | NPC1RAB9AMAPTPOLBMEN1 | |
| SCHEMBL10506692 | 0.83 | ALDH1A1 (0.48) | NPC1RAB9AMAPTPOLBMEN1 | |
| SCHEMBL10507083 | 0.81 | KAT6A (0.46) | NPC1RAB9AMAPTPOLBMEN1 | |
| SCHEMBL27826514 | 0.81 | CYP3A4 (0.48) | NPC1RAB9AMAPTPOLBMEN1 | |
| SCHEMBL10810843 | 0.81 | POLB (0.53) | POLBMEN1KMT2ANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4699949-A | Hardening of acid-hardenable compositions containing a blocked hardening catalyst, using heat | CIBA-GEIGY CORPORATION (US) | 1987-10-13 | — | — | US | disclosed |