Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10452675 | 0.92 | NPSR1 (0.44) | NPSR1ALDH1A1MAPTNPC1LMNA | |
| SCHEMBL10505584 | 0.85 | ENPP3 (0.48) | NPSR1ALDH1A1MAPTNPC1LMNA | |
| SCHEMBL10813751 | 0.85 | NPC1 (0.61) | NPSR1ALDH1A1MAPTNPC1LMNA | |
| SCHEMBL10811773 | 0.85 | TDP1 (0.56) | NPSR1ALDH1A1MAPTNPC1LMNA | |
| SCHEMBL10708800 | 0.83 | ALDH1A1 (0.42) | NPSR1ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL60545 | 0.82 | CYP3A4 (0.51) | NPSR1ALDH1A1MAPTNPC1LMNA | |
| SCHEMBL27826514 | 0.82 | CYP3A4 (0.48) | NPSR1ALDH1A1MAPTNPC1LMNA | |
| SCHEMBL9128620 | 0.82 | MAPT (0.55) | NPSR1ALDH1A1MAPTNPC1KMT2A | |
| SCHEMBL10817196 | 0.81 | PLK1 (0.44) | ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL7122948 | 0.77 | ALDH1A1 (0.51) | NPSR1ALDH1A1MAPTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6664021-B1 | Acid generator and silicon-containing polyimide ester precursor comprising partially esterified silicon-containing polyamic ester; radiating with light | CHISSO CORPORATION (JP) | 2003-12-16 | — | — | US | disclosed |
| US-5449705-A | Silicon-containing polyamic acid derivative and photosensitive resin composition using it | CHISSO CORPORATION (JP) | 1995-09-12 | — | — | US | disclosed |
| US-5442024-A | Polyamic acid having a crosslinkable silane group or copolymerized with a polysiloxane and a compound generating an acid catalyst to effect imidation upon radiating; films; photoresists; shrinkage inhibition; resolution; adhesion | CHISSO CORPORATION (JP) | 1995-08-15 | — | — | US | disclosed |