Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR6 | O00574 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | ARG1 | P05089 | 1/20 | 0.42 |
| ▸ | ARG2 | P78540 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3881487 | 0.93 | DRD2 (0.48) | CXCR6DRD2DRD4DRD3ARG1 | |
| SCHEMBL3881484 | 0.93 | DRD2 (0.48) | CXCR6DRD2DRD4DRD3ARG1 | |
| SCHEMBL30833195 | 0.93 | DRD2 (0.48) | CXCR6DRD2DRD4DRD3ARG1 | |
| SCHEMBL10817485 | 0.85 | OPRK1 (0.52) | OPRK1DRD2DRD4DRD3MAPT | |
| SCHEMBL10812514 | 0.85 | OPRK1 (0.58) | OPRK1MAPTALDH1A1 | |
| SCHEMBL9023345 | 0.85 | CHRM2 (0.54) | OPRK1ALDH1A1LMNA | |
| SCHEMBL8120312 | 0.85 | CHRM2 (0.54) | OPRK1ALDH1A1LMNA | |
| SCHEMBL20967986 | 0.85 | CHRM2 (0.54) | OPRK1ALDH1A1LMNA | |
| SCHEMBL27676903 | 0.84 | DRD2 (0.51) | CXCR6OPRK1DRD2DRD4DRD3 | |
| SCHEMBL9413102 | 0.82 | DRD4 (0.47) | CXCR6DRD2DRD4DRD3ARG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0076592-B1 | AZABICYCLO-(3,3,1)-NONYLBENZAMIDE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1987-01-28 | — | — | EP | disclosed |
| US-4560757-A | 9-Azabicyclo(3.3.1) nonane intermediates for compounds useful in the treatment of CNS disorders | BEECHAM GROUP P.L.C. (GB) | 1985-12-24 | — | — | US | disclosed |
| US-4472413-A | PSYCHOLOGICAL DISORDERS | BEECHAM GROUP P.L.C. (GB) | 1984-09-18 | — | — | US | disclosed |