Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | ARG1 | P05089 | 1/20 | 0.46 |
| ▸ | ARG2 | P78540 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3881487 | 1.00 | DRD2 (0.48) | DRD2DRD4DRD3ARG1ARG2 | |
| SCHEMBL3881484 | 1.00 | DRD2 (0.48) | DRD2DRD4DRD3ARG1ARG2 | |
| SCHEMBL10815249 | 0.93 | CXCR6 (0.46) | DRD2DRD4DRD3ARG1ARG2 | |
| Trifluoroacetic Acid SCHEMBL30201437 | 0.86 | ARG1 (0.54) | DRD2DRD4DRD3ARG1ARG2 | |
| Trifluoroacetic Acid SCHEMBL30201455 | 0.86 | ARG1 (0.54) | DRD2DRD4DRD3ARG1ARG2 | |
| SCHEMBL9413102 | 0.85 | DRD4 (0.47) | DRD2DRD4DRD3ARG1ARG2 | |
| SCHEMBL9413099 | 0.85 | DRD4 (0.47) | DRD2DRD4DRD3ARG1ARG2 | |
| SCHEMBL30833222 | 0.84 | DRD2 (0.51) | DRD2DRD4DRD3MAPTLTA4H | |
| SCHEMBL3880873 | 0.84 | DRD2 (0.51) | DRD2DRD4DRD3MAPTLTA4H | |
| SCHEMBL3880869 | 0.84 | DRD2 (0.51) | DRD2DRD4DRD3MAPTLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117729914-A | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2024-03-19 | — | — | CN | disclosed |