Methallibure

Methallibure

SCHEMBL393014

C=CC(C)NC(=S)NNC(=S)NC

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methallibure SCHEMBL4312430 0.98 GAA (0.30) GAA
SCHEMBL3799164 0.89
Methallibure SCHEMBL6614118 0.87 ATM (0.45) GAA
SCHEMBL6947071 0.82 ALDH1A1 (0.40) GAA
SCHEMBL10816655 0.80 ALDH1A1 (0.35) GAA
SCHEMBL11378848 0.75 ALDH1A1 (0.43) GAA
SCHEMBL21239911 0.74
SCHEMBL10815551 0.74
SCHEMBL11368868 0.71 LMNA (0.41) GAA
SCHEMBL10907102 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 923 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12631240-B2 Parabolic tooth trace gear mechanism with combined tooth profile of end face circular arc and parabola GUANGDONG OCEAN UNIVERSITY (CN) 2026-05-19 US claimed
US-20260016067-A1 Parabolic tooth trace gear mechanism with combined tooth profile of end face circular arc and parabola UNIV GUANGDONG OCEAN (CN) 2026-01-15 US claimed
EP-4659061-A1 SINGLE-MODE OPTICAL FIBERS WITH LOW CUTOFF WAVELENGTH AND LOW BEND LOSS Corning Incorporated (US) 2025-12-10 EP claimed
US-12372437-B1 Device and method for testing starting characteristics of refrigeration compressor with adjustable system volume ZHEJIANG UNIVERSITY OF TECHNLOGY (CN) 2025-07-29 US claimed
CN-120044851-A Intelligent network train group formation control and intermittent control method under zero trust environment 苏州科技大学 2025-05-27 CN claimed
CN-119990901-A Calculation method for taking over interaction performance of driver in non-driving posture 合肥工业大学 2025-05-13 CN claimed
EP-4548137-A1 COMPLIANT OPTICAL FIBER HAVING UPDOPED OUTER CLADDING Corning Incorporated (US) 2025-05-07 EP claimed
CN-119741157-A Competition type learning evaluation method and system based on multiple-weight TOPSIS method 长春工程学院 2025-04-01 CN claimed
EP-4515308-A1 COMPLIANT OPTICAL FIBER Corning Incorporated (US) 2025-03-05 EP claimed
CN-119532286-A Hydraulic mechanical transmission device control method based on optimal track optimization 北京长城航空测控技术研究所有限公司 2025-02-28 CN claimed
EP-2324380-A1 MULTIMODE FIBER WITH AT LEAST DUAL CLADDING Corning Incorporated (US) 2011-05-25 EP claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101767424-A Injection molding machine and injection molding method SUZHOU JVLIAN TECHNOLOGY CO LT 2010-07-07 CN claimed
WO-2010019222-A1 MULTIMODE FIBER WITH AT LEAST DUAL CLADDING CORNING INCORPORATED (US) 2010-02-18 WO claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
EP-1728380-A1 METHOD FOR THE EARLY IDENTIFICATION OF A DEVIATION IN THE PRINTED IMAGES THAT HAVE BEEN CREATED BY A PRINTING PRESS DURING CONTINUOUS PRODUCTION Koenig & Bauer AG (DE) 2006-12-06 EP claimed
WO-2005094054-A1 METHOD FOR THE EARLY IDENTIFICATION OF A DEVIATION IN THE PRINTED IMAGES THAT HAVE BEEN CREATED BY A PRINTING PRESS DURING CONTINUOUS PRODUCTION KOENIG & BAUER AKTIENGESELLSCHAFT (DE) 2005-10-06 WO claimed
US-20040248036-A1 Rewritable optical recording medium and optical recoding method MITSUBISHI CHEMICAL CORPORATION (JP) 2004-12-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12631240-B2 Parabolic tooth trace gear mechanism with combined tooth profile of end face circular arc and parabola PARL, TAS2R39, STRA6 GAA 4591/4885
US-20260016067-A1 Parabolic tooth trace gear mechanism with combined tooth profile of end face circular arc and parabola PARL, TAS2R39, STRA6 GAA 4597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.