Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 2/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | TACR2 | P21452 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487316 | 1.00 | STS (0.42) | STSPLA2G4AALDH1A1LMNACYP3A4 | |
| SCHEMBL10487306 | 0.84 | ESR1 (0.41) | STSPLA2G4AALDH1A1LMNACYP3A4 | |
| SCHEMBL19665417 | 0.82 | STS (0.45) | STSPLA2G4AALDH1A1LMNACYP3A4 | |
| SCHEMBL10487303 | 0.82 | PLA2G4A (0.34) | STSPLA2G4AALDH1A1LMNACYP3A4 | |
| SCHEMBL10487314 | 0.81 | THRA (0.41) | CYP3A4THRBTHRAPTGS2PPARG | |
| SCHEMBL10816668 | 0.81 | THRA (0.41) | CYP3A4THRBTHRAPTGS2PPARG | |
| SCHEMBL11895980 | 0.80 | RXRB (0.31) | — | |
| SCHEMBL11771239 | 0.78 | ALDH1A1 (0.55) | ALDH1A1LMNACYP3A4THRBTHRA | |
| SCHEMBL11159991 | 0.78 | ALDH1A1 (0.55) | ALDH1A1LMNACYP3A4THRBTHRA | |
| SCHEMBL11871536 | 0.78 | ALDH1A1 (0.55) | ALDH1A1LMNACYP3A4THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4707509-A | Tris-organophosphite compositions having improved hydrolytic stability | ARGUS CHEMICAL CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |
| EP-0167969-A2 | Tris-organophosphite compositions having improved hydrolytic stability | Argus Chemical Corporation (US) | 1986-01-15 | — | — | EP | disclosed |