Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | HPN | P05981 | 1/20 | 0.46 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10814864 | 0.87 | MAPT (0.60) | MAPTRAB9AHPGDNPC1GFER | |
| SCHEMBL10813878 | 0.85 | MAPT (0.53) | MAPTRAB9AHPGDNPC1GFER | |
| SCHEMBL10812098 | 0.84 | ALDH1A1 (0.47) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL10815062 | 0.79 | RAB9A (0.48) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL27619397 | 0.77 | RAB9A (0.70) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL10818322 | 0.76 | RAB9A (0.63) | MAPTRAB9AHPGDNPC1GFER | |
| SCHEMBL15330680 | 0.73 | MAPT (0.51) | MAPTRAB9AHPGDNPC1GFER | |
| SCHEMBL3586307 | 0.72 | MAPT (0.56) | MAPTRAB9AHPGDNPC1GFER | |
| SCHEMBL31276114 | 0.72 | MAPT (0.62) | MAPTRAB9AHPGDNPC1GFER | |
| SCHEMBL14966296 | 0.72 | RAB9A (0.46) | MAPTRAB9AHPGDNPC1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0102510-B1 | SUBSTITUTED 4-FLUOROPYRIDAZ-6-ONES | BASF Aktiengesellschaft (DE) | 1987-10-07 | — | — | EP | disclosed |
| EP-0102510-A1 | Substituted 4-fluoropyridaz-6-ones | BASF Aktiengesellschaft (DE) | 1984-03-14 | — | — | EP | disclosed |