Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | GFER | P55789 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31276130 | 0.85 | PTGS1 (0.51) | MAPTRAB9ANPC1HPGDGFER | |
| SCHEMBL10814864 | 0.79 | MAPT (0.60) | MAPTRAB9ANPC1HPGDGFER | |
| SCHEMBL31276196 | 0.79 | LMNA (0.56) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL31276289 | 0.77 | MAPK14 (0.46) | MAPTRAB9ANPC1HPGDMAPK14 | |
| SCHEMBL31276388 | 0.76 | LMNA (0.53) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL4217545 | 0.74 | RAB9A (0.48) | MAPTRAB9ANPC1CYP1A2SMN1; SMN2 | |
| SCHEMBL1846495 | 0.73 | MAPT (0.61) | MAPTRAB9ANPC1HPGDGFER | |
| SCHEMBL30725849 | 0.73 | MAPT (0.57) | MAPTRAB9ANPC1HPGDGFER | |
| SCHEMBL15330680 | 0.73 | MAPT (0.51) | MAPTRAB9ANPC1HPGDGFER | |
| SCHEMBL10817035 | 0.72 | MAPT (0.50) | MAPTRAB9ANPC1HPGDGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119019332-A | 1, 5-Disubstituted-4-bromopyrazole compound and preparation method and application thereof | 赣南师范大学 | 2024-11-26 | — | — | CN | disclosed |