Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL11586582 | 0.91 | CA1 (0.50) | CA1CA4CA2 | |
| Potassium Ion SCHEMBL44034 | 0.91 | CA1 (0.50) | CA1CA4CA2 | |
| Potassium Ion SCHEMBL44036 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL8749562 | 0.83 | CA1 (0.43) | CA1CA4CA2 | |
| Hydrochloric Acid SCHEMBL9808348 | 0.83 | — | — | |
| SCHEMBL11586203 | 0.82 | CA1 (0.60) | CA1CA4CA2 | |
| SCHEMBL123095 | 0.82 | — | — | |
| Potassium Ion SCHEMBL1332522 | 0.82 | — | — | |
| Potassium Ion SCHEMBL1331713 | 0.82 | — | — | |
| Potassium Ion SCHEMBL1284 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120097439-A1 | MODIFIED POLYIMIDE AND METHOD FOR PRODUCING MODIFIED POLYIMIDE | PI R&D CO., LTD. (JP) | 2012-04-26 | — | — | US | disclosed |
| US-20120097435-A1 | PHOTOSENSITIVE MODIFIED POLYIMIDE RESIN COMPOSITION AND USE THEREOF | PI R&D CO., LTD. (JP) | 2012-04-26 | — | — | US | disclosed |
| EP-2431400-A2 | MODIFIED POLYIMIDE AND METHOD FOR PRODUCING MODIFIED POLYIMIDE | PI R & D Co. Ltd (JP) | 2012-03-21 | — | — | EP | disclosed |
| EP-2426557-A1 | PHOTOSENSITIVE MODIFIED POLYIMIDE RESIN COMPOSITION AND USE THEREOF | PI R & D Co. Ltd (JP) | 2012-03-07 | — | — | EP | disclosed |