Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | PKLR | P30613 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823450 | 0.85 | CA2 (0.49) | CA2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10823773 | 0.84 | IDH1 (0.45) | PKMCA12CA1CA2CA9 | |
| SCHEMBL10823661 | 0.84 | MEN1 (0.43) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL10823647 | 0.83 | IDH1 (0.44) | PKMPKLRCA12CA1CA2 | |
| SCHEMBL10823757 | 0.82 | PRMT1 (0.62) | PKMPKLRCA12CA1CA2 | |
| SCHEMBL10823443 | 0.82 | MEN1 (0.44) | CA12CA1CA2CA9IDH1 | |
| SCHEMBL10823369 | 0.82 | NT5E (0.47) | CA12CA1CA2CA9IDH1 | |
| SCHEMBL11343138 | 0.82 | HPSE (0.46) | PKMPKLRCA12CA1CA2 | |
| SCHEMBL10823710 | 0.81 | MEN1 (0.50) | PKMIDH1MEN1KMT2AALDH1A1 | |
| SCHEMBL10823410 | 0.81 | IDH1 (0.61) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |