Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | CYTH2 | Q99418 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823568 | 0.84 | LMNA (0.44) | CA2GFERPOLBGAATIMP3 | |
| SCHEMBL10823472 | 0.83 | PTGES (0.46) | MEN1KMT2APTGESCYTH2CA12 | |
| SCHEMBL10823661 | 0.82 | MEN1 (0.43) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL10823553 | 0.82 | PTGES (0.50) | MEN1KMT2APTGESCA12CA1 | |
| SCHEMBL10823376 | 0.82 | PKM (0.46) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL10823575 | 0.81 | MEN1 (0.48) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL10823352 | 0.81 | PTGES (0.41) | MEN1KMT2APTGESCYTH2CA12 | |
| SCHEMBL11342247 | 0.81 | MAPT (0.46) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL10823660 | 0.80 | IDH1 (0.53) | IDH1 | |
| SCHEMBL10823744 | 0.80 | PRMT1 (0.44) | MEN1KMT2APTGESCYTH2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |