Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.43 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.43 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823349 | 0.87 | IDH1 (0.43) | IDH1CA12CA1CA2CA9 | |
| SCHEMBL10823428 | 0.85 | TNNI3 (0.49) | CA1CA2TNNI3TNNT2TNNC1 | |
| SCHEMBL10823376 | 0.84 | PKM (0.46) | IDH1CA12CA1CA2CA9 | |
| SCHEMBL10823647 | 0.84 | IDH1 (0.44) | IDH1CA12CA1CA2CA9 | |
| SCHEMBL10823535 | 0.84 | EP300 (0.43) | IDH1CA12CA1CA2CA9 | |
| SCHEMBL10823352 | 0.83 | PTGES (0.41) | IDH1CA12CA1CA2CA9 | |
| SCHEMBL10823779 | 0.83 | EP300 (0.49) | IDH1CA12CA1CA2CA9 | |
| SCHEMBL10823757 | 0.83 | PRMT1 (0.62) | IDH1CA12CA1CA2CA9 | |
| SCHEMBL10823460 | 0.82 | CA12 (0.43) | CA12CA1CA2CA9HKDC1 | |
| SCHEMBL11338942 | 0.81 | HPSE (0.52) | IDH1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |