Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | UQCRB | P14927 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823508 | 0.89 | MEN1 (0.46) | LMNAKMT2ACA2MEN1ALOX12 | |
| SCHEMBL10823453 | 0.86 | LMNA (0.46) | LMNAKMT2AALDH1A1CA2FASN | |
| SCHEMBL10823430 | 0.84 | IDH1 (0.55) | — | |
| SCHEMBL10823499 | 0.84 | KMT2A (0.42) | UQCRBKMT2AALDH1A1CA2MEN1 | |
| SCHEMBL10823342 | 0.83 | KMT2A (0.45) | LMNAKMT2AALDH1A1CA2FASN | |
| SCHEMBL11351667 | 0.82 | CD40 (0.47) | KMT2AALDH1A1CA2MEN1CA1 | |
| SCHEMBL10823418 | 0.81 | UQCRB (0.47) | LMNAUQCRBKMT2AALDH1A1CA2 | |
| SCHEMBL10823346 | 0.80 | CHEK1 (0.45) | LMNAUQCRBKMT2ACA2MEN1 | |
| SCHEMBL10823412 | 0.79 | AURKB (0.47) | LMNAUQCRBKMT2AALDH1A1MEN1 | |
| SCHEMBL11346155 | 0.77 | KMT2A (0.40) | KMT2ACA2MEN1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |