Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | GHSR | Q92847 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823567 | 0.90 | IDH1 (0.48) | KMT2ALMNAMEN1ALOX12PRMT1 | |
| SCHEMBL10823479 | 0.87 | HSD17B2 (0.46) | KMT2AALDH1A1LMNAGHSRMEN1 | |
| SCHEMBL10823535 | 0.84 | EP300 (0.43) | KMT2AALDH1A1LMNAGHSRMEN1 | |
| SCHEMBL10823384 | 0.83 | LMNA (0.46) | KMT2AALDH1A1LMNAGHSRMEN1 | |
| SCHEMBL10823559 | 0.83 | LMNA (0.50) | KMT2AALDH1A1LMNAGHSRMEN1 | |
| SCHEMBL11341156 | 0.81 | TIMP3 (0.48) | KMT2AALDH1A1MEN1PRMT1MAPT | |
| SCHEMBL10823412 | 0.81 | AURKB (0.47) | KMT2AALDH1A1LMNAMEN1HTT | |
| SCHEMBL10823362 | 0.81 | MEN1 (0.46) | KMT2AALDH1A1LMNAMEN1HTT | |
| SCHEMBL10823718 | 0.81 | HKDC1 (0.48) | KMT2AALDH1A1LMNAMEN1PRMT1 | |
| SCHEMBL10823428 | 0.80 | TNNI3 (0.49) | KMT2AALDH1A1LMNAMEN1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |