Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | NEK2 | P51955 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | IDH2 | P48735 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823538 | 0.92 | MEN1 (0.44) | MEN1KMT2ACHEK1CDK8NEK2 | |
| SCHEMBL10823359 | 0.86 | CA12 (0.45) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL10823478 | 0.84 | LMNA (0.52) | MEN1KMT2ACA2ENPP2HTT | |
| SCHEMBL10823573 | 0.83 | MCL1 (0.45) | MEN1KMT2AHKDC1GAAKDM4E | |
| SCHEMBL10823633 | 0.83 | CA12 (0.42) | MEN1KMT2ACHEK1CDK8NEK2 | |
| SCHEMBL10823574 | 0.83 | CA12 (0.45) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL11424721 | 0.83 | DHODH (0.44) | MEN1KMT2APOLBGAAALDH1A1 | |
| SCHEMBL10823622 | 0.80 | HPSE (0.40) | MEN1KMT2ACHEK1CDK8NEK2 | |
| SCHEMBL10823437 | 0.80 | CASP6 (0.44) | MEN1KMT2ACHEK1CDK8NEK2 | |
| SCHEMBL10823535 | 0.80 | EP300 (0.43) | MEN1KMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |