Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.48 |
| ▸ | EP300 | Q09472 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GHSR | Q92847 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | FASN | P49327 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823709 | 0.91 | LMNA (0.52) | LMNAPRMT3EP300PRMT6PRMT1 | |
| SCHEMBL10823625 | 0.85 | IDH1 (0.57) | — | |
| SCHEMBL10823738 | 0.84 | MEN1 (0.44) | EP300MEN1KMT2AHTTENPP2 | |
| SCHEMBL11338609 | 0.82 | PRMT1 (0.49) | PRMT3EP300PRMT6PRMT1MEN1 | |
| SCHEMBL10823559 | 0.82 | LMNA (0.50) | LMNAPRMT1MEN1KMT2AGAA | |
| SCHEMBL10823378 | 0.80 | MEN1 (0.49) | LMNAMEN1KMT2AHTTGAA | |
| SCHEMBL10823663 | 0.80 | LMNA (0.47) | LMNAEP300MEN1KMT2AHTT | |
| SCHEMBL10823344 | 0.80 | EP300 (0.50) | LMNAEP300MEN1KMT2AHTT | |
| SCHEMBL10823548 | 0.79 | MEN1 (0.49) | LMNAPRMT3EP300PRMT6PRMT1 | |
| SCHEMBL10955372 | 0.79 | ENPP2 (0.47) | PRMT3EP300PRMT6PRMT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |